Brandenburg J H, Finch W W, Kirkham W R
Otolaryngology. 1978 Sep-Oct;86(5):ORL-739-42. doi: 10.1177/019459987808600513.
This paper presents a case report of a 67-year-old man who was seen in the Otolaryngology Clinic, University of Wisconsin Medical Center with a seven-month history of dyspnea and laryngeal stridor. On examination there were several slightly tender firm submucosal nodules in the soft palate and left tonsilar area and a 1.5-cm polypoid subglottic mass arising from the body of the cricoid cartilage. Because of the marked airway obstruction, a tracheotomy was necessary. The laryngeal polypoid mass was removed and biopsies were obtained from the submucosal nodular masses of the palate. Microscopic examination of the tissue revealed the lesions to be caseating granulomas, and actinomycosis was identified on the cultures. The patient received long-term penicillin therapy and has remained asymptomatic. A discussion of the biologic and clinical aspects of actinomycosis is included. A review of the literature revealed only one other description of endolaryngeal actinomycosis.
本文报告了一例67岁男性病例，该患者因呼吸困难和喉喘鸣7个月就诊于威斯康星大学医学中心耳鼻喉科诊所。检查发现软腭和左扁桃体区域有几个稍有压痛的坚实黏膜下结节，环状软骨体有一个1.5厘米的息肉样声门下肿物。由于气道严重阻塞，需要进行气管切开术。切除了喉部息肉样肿物，并从腭部黏膜下结节肿物处取了活检。组织显微镜检查显示病变为干酪样肉芽肿，培养物中鉴定出放线菌病。患者接受了长期青霉素治疗，至今仍无症状。文中还讨论了放线菌病的生物学和临床方面。文献回顾显示，仅有另一篇关于喉内放线菌病的描述。
