Januszewicz W, Filipecki S, Baczko A, Wocial D, Andziak E, Pruszynski B, Rajszys R
Cor Vasa. 1975;17(1):32-42.
Renal venous and peripheral plasma renin activities were determined in 29 operated patients with renovascular hypertension and in 10 patients with essential hypertension. The majority of patients with renovascular hypertension exhibited elevated peripheral plasma renin activity, but the most striking increase of renin activity was demonstrated in the venous effluent of the involved kidney. Using data obtained in patients with essential hypertension, the ratio of renal vein renin activity not exceeding 1.4 was assumed normal. In patients with renovascular hypertension, the values above 1.4 were accepted as lateralizing ratios. In 78.6 % of patients with unilateral renal artery stenosis and a lateralizing renal vein renin ratio, normotension or improvement of blood pressure control were obtained post-operatively. The discussion emphasis the importances of renal vein renin estimations with the calculation of renal vein ratio for determining the functional significance of renal artery stenosis and for predicting the surgical outcome
对29例接受手术的肾血管性高血压患者和10例原发性高血压患者测定了肾静脉和外周血浆肾素活性。大多数肾血管性高血压患者外周血浆肾素活性升高，但受累肾脏静脉流出液中肾素活性的升高最为显著。利用原发性高血压患者的数据，肾静脉肾素活性比值不超过1.4被认为是正常的。在肾血管性高血压患者中，高于1.4的值被作为定位比值。在78.6%的单侧肾动脉狭窄且肾静脉肾素比值具有定位意义的患者中，术后血压恢复正常或血压控制得到改善。讨论强调了肾静脉肾素测定以及计算肾静脉比值对于确定肾动脉狭窄的功能意义和预测手术结果的重要性。
