Godard A
Helv Paediatr Acta. 1977 Jun;32(1):49-57.
Renal-vein renin was determined in 55 children with renovascular or renal hypertension, 33 of whom being treated surgically. The overall cure rate after surgery was 87.9%. Of 23 patients having a renal-vein renin ratio greater than 1.5, 20 were operated successfully, but 9 of 10 operated patients with a ratio of less than 1.5 also benefited from surgery. Taking into account the frequency of "false-negative ratios" (27.3%) and the potential risks of catheterization, it is suggested that renal-vein renin measurements are not useful as a routine procedure for investigation of a child with renovascular hypertension.
对55例患有肾血管性或肾性高血压的儿童进行了肾静脉肾素测定，其中33例接受了手术治疗。手术后的总体治愈率为87.9%。在23例肾静脉肾素比值大于1.5的患者中，20例手术成功，但在10例比值小于1.5的手术患者中，也有9例从手术中获益。考虑到“假阴性比值”的发生率（27.3%）以及导管插入术的潜在风险，建议肾静脉肾素测定不作为儿童肾血管性高血压调查的常规程序。
