Takusa Y, Hori D, Saito K, Kanai R, Sejima H, Kimura M, Kishi K, Yamaguchi S
Department of Pediatrics, Shimane Medical University, Izumo, Shimane.
No To Hattatsu. 2001 Jul;33(4):351-6.
A 5-year-old boy with a peculiar type of post-encephalitic/encephalopathic epilepsy is reported. He had been healthy showing normal development before its onset. Five days after the onset of an upper respiratory infection, he had a severe generalized seizure, that evolved into intractable seizures. They were highly resistant to almost all anticonvulsants and occasionally resulted in status epilepticus. High-dose phenobarbital therapy successfully controlled the convulsions, but was discontinued because of drug-induced aplastic anemia. Alternative bromide therapy was markedly effective in controlling the seizures.
报告了一名患有特殊类型的脑炎后/脑病性癫痫的5岁男孩。在发病前他一直健康，发育正常。上呼吸道感染发病5天后，他出现了严重的全身性癫痫发作，并演变为难治性癫痫发作。这些发作对几乎所有抗惊厥药物都具有高度抗性，偶尔会导致癫痫持续状态。高剂量苯巴比妥治疗成功控制了惊厥，但因药物性再生障碍性贫血而停药。替代的溴化物治疗在控制癫痫发作方面显著有效。
