Harris R J
J Periodontol. 2001 Jul;72(7):932-8. doi: 10.1902/jop.2001.72.7.932.
The importance of keratinized tissue is a controversial subject. However, in some situations most clinicians would agree that surgical procedures to increase the amount of keratinized tissue without root coverage are indicated. In this study, 3 surgical procedures were compared in their ability to increase the width of keratinized tissue. They are: the epithelized autogenous masticatory mucosa graft (free gingival graft), autogenous predominately connective tissue graft (connective tissue graft), and acellular dermal matrix.
Forty-five patients referred for treatment of areas with inadequate keratinized tissue were randomly assigned into 1 of 3 groups of 15 each. Each group was treated with 1 of the 3 surgical procedures to increase the width of keratinized tissue. The width of keratinized tissue pre- and postsurgery was evaluated.
All 3 groups started with a similar width of keratinized tissue. All of the surgical procedures resulted in a statistically significant increase in the width of keratinized tissue: free gingival graft, 4.1 mm; connective tissue graft, 3.6 mm; and acellular dermal matrix, 4.1 mm.
A statistically significant increase in the amount of keratinized tissue was obtained with all 3 surgical procedures evaluated.
角化组织的重要性是一个存在争议的话题。然而，在某些情况下，大多数临床医生会认同，在不进行牙根覆盖的情况下，需要采取手术来增加角化组织的量。在本研究中，对三种手术增加角化组织宽度的能力进行了比较。它们分别是：上皮化自体咀嚼黏膜移植（游离龈瓣移植）、自体主要为结缔组织移植（结缔组织移植）和脱细胞真皮基质。
45例因角化组织不足前来治疗的患者被随机分为3组，每组15例。每组接受三种增加角化组织宽度的手术之一进行治疗。评估手术前后角化组织的宽度。
所有3组的角化组织起始宽度相似。所有手术均使角化组织宽度在统计学上显著增加：游离龈瓣移植增加4.1毫米；结缔组织移植增加3.6毫米；脱细胞真皮基质增加4.1毫米。
所有评估的三种手术均使角化组织量在统计学上显著增加。
