Jenabian Niloofar, Yazdanpanahbahabadi Mohadese, Haghpanah Aski Parya, Bijani Ali
Department of Periodontics, Dental School, Babol University of Medical Sciences, Babol, Iran.
Department of Non-communicable Pediatric Diseases Research Center, School of Dentistry, Babol University of Medical Sciences, Babol, Iran.
J Adv Periodontol Implant Dent. 2020 Apr 21;12(1):11-17. doi: 10.34172/japid.2020.004. eCollection 2020.
This study aimed to evaluate the effect of acellular dermal matrix allograft (ADMA) for the treatment of gingival recession as a substitute for subepithelial connective tissue graft (SCTG).
In this controlled clinical trial, 18 teeth were selected in nine subjects with bilateral gingival recession. One side was treated with SCTG and a coronally displaced flap as the control group, and the other side was treated with ADMA and a coronally displaced flap as the test group. Probing pocket depth (PPD), clinical attachment level, vertical recession depth, recession width, gingival thickness, keratinized tissue width, and the root coverage percentage were measured before the surgery and at 1-, 3-, and 6-month postoperative intervals. The healing index, pain index, and patient satisfaction were also investigated. The data were analyzed with a general linear model (GLM) repeated measures and paired t-test.
All the parameters improved except for PPD; however, a comparison between the groups did not reveal statistically significant differences. Only root coverage percentage and pain index were significantly lower in the test group. The average percentage of root coverage in the control and test groups were 82.01±16.62% and 64.44±9.4%, respectively.
Both methods resulted in improvements in the clinical results. However, the use of the ADMA led to less pain and root coverage in comparison with the SCTG method.
本研究旨在评估同种异体脱细胞真皮基质（ADMA）作为替代上皮下结缔组织移植（SCTG）治疗牙龈退缩的效果。
在这项对照临床试验中，选取9名双侧牙龈退缩受试者的18颗牙齿。一侧采用SCTG联合冠向移位瓣治疗作为对照组，另一侧采用ADMA联合冠向移位瓣治疗作为试验组。在手术前以及术后1个月、3个月和6个月时测量探诊深度（PPD）、临床附着水平、垂直退缩深度、退缩宽度、牙龈厚度、角化组织宽度和牙根覆盖百分比。还调查愈合指数、疼痛指数和患者满意度。数据采用广义线性模型（GLM）重复测量和配对t检验进行分析。
除PPD外，所有参数均有所改善；然而，组间比较未显示出统计学上的显著差异。仅试验组的牙根覆盖百分比和疼痛指数显著较低。对照组和试验组的平均牙根覆盖百分比分别为82.01±16.62%和64.44±9.4%。
两种方法均使临床结果得到改善。然而，与SCTG方法相比，使用ADMA导致的疼痛和牙根覆盖较少。
