Garcia-Sevilla J A, Badia A, Laporte J
Eur J Pharmacol. 1975 Apr;31(2):363-6. doi: 10.1016/0014-2999(75)90061-8.
Uptake mechanisms in the rat vas deferens have not yet been thoroughly investigated. In this study we show that uptake inhibition by cocaine, amantadine and desmethylimipramine induces increases in sensitivity that are greater for adrenaline than for noradrenaline. However, this does not occur when guanethidine is used. These results are clearly in disagreement with the neuronal uptake hypothesis. Uptake mechanisms in the rat vas deferens may be different from those of other tissues.
大鼠输精管的摄取机制尚未得到充分研究。在本研究中，我们发现可卡因、金刚烷胺和去甲丙咪嗪对摄取的抑制作用会导致敏感性增加，对肾上腺素的敏感性增加幅度大于去甲肾上腺素。然而，使用胍乙啶时则不会出现这种情况。这些结果显然与神经元摄取假说不一致。大鼠输精管的摄取机制可能与其他组织不同。
