Voltarelli J C, Ahmed H, Paton E J, Stracieri A B, Holman P, Bashey A, Coutinho M, Simoes B P, Ball E D, Carrier E
Bone Marrow Transplantation Unit, University Hospital, School of Medicine of Ribeirão Preto, University of São Paulo, Brazil.
Bone Marrow Transplant. 2001 Jul;28(1):97-9. doi: 10.1038/sj.bmt.1703080.
We report two cases of refractory chronic graft-versus-host disease after donor lymphocyte infusions in which the skin lesions improved dramatically with the use of intravenous pulses of lidocaine. This form of therapy has been used successfully for the cutaneous involvement of scleroderma and may have vasodilator and anti-inflammatory effects.
我们报告了两例在输注供体淋巴细胞后出现难治性慢性移植物抗宿主病的病例，其中皮肤病变在使用静脉注射利多卡因脉冲后显著改善。这种治疗方式已成功用于硬皮病的皮肤受累情况，可能具有血管舒张和抗炎作用。
