黄体中期血清催乳素对体外受精-胚胎移植术后妊娠结局的影响：一项初步研究。
Influence of midluteal serum prolactin on outcome of pregnancy after IVF-ET: a preliminary study.
作者信息
Ozaki T, Takahashi K, Kurioka H, Miyazaki K
机构信息
Department of Obstetrics and Gynecology, Shimane Medical University, 89-1, Enya-cho, Izumo 693-8501, Japan.
出版信息
J Assist Reprod Genet. 2001 Jul;18(7):387-90. doi: 10.1023/a:1016674523317.
Abstract
PURPOSE
To investigate the relationship between serum prolactin levels in the midluteal phase and the prognosis of pregnancy after IVF-ET.
DESIGN
Prospective study;
SETTING
Shimane Medical University Hospital;
PATIENTS
29 patients completing their 34th IVF cycle; and
MAIN OUTCOME MEASURES
Serum levels of prolactin, estradiol-17 beta, and progesterone in the midluteal phase.
RESULTS
Midluteal prolactin levels were significantly lower in patients with early pregnancy loss than in the successful pregnancy group. The mean progesterone/prolactin ratio and the estradiol-17 beta/prolactin ratio were highest in patients with early pregnancy loss and were lowest in patients with successful pregnancies.
CONCLUSIONS
Findings of this study suggest that measurement of the serum prolactin concentration in the midluteal phase is useful for predicting the outcome of IVF-ET.
摘要
目的
探讨黄体中期血清催乳素水平与体外受精-胚胎移植（IVF-ET）后妊娠预后的关系。
设计
前瞻性研究；
地点
岛根医科大学医院；
患者
完成第34次IVF周期的29例患者；
主要观察指标
黄体中期血清催乳素、雌二醇-17β和孕酮水平。
结果
早期妊娠丢失患者的黄体中期催乳素水平显著低于成功妊娠组。早期妊娠丢失患者的平均孕酮/催乳素比值和雌二醇-17β/催乳素比值最高，成功妊娠患者的该比值最低。
结论
本研究结果表明，测量黄体中期血清催乳素浓度有助于预测IVF-ET的结局。
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本文引用的文献
1
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2
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Am J Obstet Gynecol. 1981 Jul 1;140(5):587-91. doi: 10.1016/0002-9378(81)90237-4.
3
Successful pregnancy in an acromegalic patient during 2-Br-alpha-ergocryptine (CB-154) therapy.一名肢端肥大症患者在接受2-溴-α-麦角隐亭（CB-154）治疗期间成功怀孕。
Acta Endocrinol (Copenh). 1982 Nov;101(3):333-8. doi: 10.1530/acta.0.1010333.
4
The periovulatory and luteal phase of conception cycles following in vitro fertilization and embryo transfer.体外受精和胚胎移植后受孕周期的围排卵期和黄体期。
Fertil Steril. 1984 Apr;41(4):530-7. doi: 10.1016/s0015-0282(16)47773-3.
5
Estrogen stimulates prolactin gene transcription by a mechanism independent of pituitary protein synthesis.雌激素通过一种独立于垂体蛋白合成的机制刺激催乳素基因转录。
Endocrinology. 1984 May;114(5):1550-7. doi: 10.1210/endo-114-5-1550.
6
Studies of prolactin secretion in human pregnancy.人类孕期催乳素分泌的研究。
Am J Obstet Gynecol. 1972 May 1;113(1):14-20. doi: 10.1016/0002-9378(72)90446-2.
7
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8
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