Kaji S, Yang P C, Kerr A B, Tang W H, Meyer C H, Macovski A, Pauly J M, Nishimura D G, Hu B S
Department of Medicine, Stanford University, California, USA.
J Am Coll Cardiol. 2001 Aug;38(2):527-33. doi: 10.1016/s0735-1097(01)01399-7.
The purpose of this study was to validate cardiac measurements derived from real-time cardiac magnetic resonance imaging (MRI) as compared with well-validated conventional cine MRI.
Although cardiac MRI provides accurate assessment of left ventricular (LV) volume and mass, most techniques have been relatively slow and required electrocardiogram (ECG) gating over many heart beats. A newly developed real-time MRI system allows continuous real-time dynamic acquisition and display without cardiac gating or breath-holding.
Fourteen healthy volunteers and nine patients with heart failure underwent real-time and cine MRI in the standard short-axis orientation with a 1.5T MRI scanner. Nonbreath-holding cine MRI was performed with ECG gating and respiratory compensation. Left ventricular end-diastolic volume (LVEDV), left ventricular endsystolic volume (LVESV), ejection fraction (EF) and LV mass calculated from the images obtained by real-time MRI were compared to those obtained by cine MRI.
The total study time including localization for real-time MRI was significantly shorter than cine MRI (8.6 +/- 2.3 vs. 24.7 +/- 3.5 min, p < 0.001). Both imaging techniques yielded good quality images allowing cardiac measurements. The measurements of LVEDV, LVESV, EF and LV mass obtained with real-time MRI showed close correlation with those obtained with cine MRI (LVEDV: r = 0.985, p < 0.001; LVESV: r = 0.994, p < 0.001; EF: r = 0.975, p < 0.001; LV mass: r = 0.977, p < 0.001).
Real-time MRI provides accurate measurements of LV volume and mass in a time-efficient manner with respect to image acquisition.
本研究旨在验证与经过充分验证的传统电影磁共振成像（MRI）相比，实时心脏MRI得出的心脏测量值。
尽管心脏MRI能准确评估左心室（LV）容积和质量，但大多数技术相对较慢，且需要在多个心跳周期进行心电图（ECG）门控。新开发的实时MRI系统可在无需心脏门控或屏气的情况下进行连续实时动态采集和显示。
14名健康志愿者和9名心力衰竭患者使用1.5T MRI扫描仪，在标准短轴方向上接受实时和电影MRI检查。非屏气电影MRI采用ECG门控和呼吸补偿进行。将实时MRI获得的图像计算得出的左心室舒张末期容积（LVEDV）、左心室收缩末期容积（LVESV）、射血分数（EF）和LV质量与电影MRI获得的结果进行比较。
包括实时MRI定位在内的总研究时间明显短于电影MRI（8.6±2.3对24.7±3.5分钟，p<0.001）。两种成像技术均能产生质量良好的图像，可进行心脏测量。实时MRI获得的LVEDV、LVESV、EF和LV质量测量值与电影MRI获得的结果密切相关（LVEDV：r = 0.985，p<0.001；LVESV：r = 0.994，p<0.001；EF：r = 0.975，p<0.001；LV质量：r = 0.977，p<0.001）。
就图像采集而言，实时MRI能高效地提供准确的LV容积和质量测量值。
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