[烧伤大鼠肾上腺中降钙素基因相关肽（CGRP）阳性神经纤维的变化]
[The changes of calcitonin gene-related peptide (CGRP)-containing nerve fibers in adrenal gland of burned rats].
作者信息
Wang B, Chen B, Hu D
机构信息
Department of Burn, Xijing Hospital of Fourth Military Medical University, Xi'an 710032.
出版信息
Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1999 Mar;15(2):99-101.
OBJECTIVE
To investigate the changes in calcitonin gene-related peptide(CGRP) within the adrenal glands medulla and cortex of the rat during early post burn period and the effect of CGRP on function of adrenal gland of burned rats.
METHODS
The rats were randomly divided into two groups: control and burned. The distribution density of CGRP containing nerve fibers and cells in medulla of adrenal gland were determined at different timepoints post burn.
RESULTS
- The CGRP-containing nerve fibers were distributed in capsule, cortex and medulla. CGRP-containing nerve fibers were associated with CGRP immunoreactive cell in medulla of adrenal glands. 2. Distribution density of CGRP-containing nerve fiber was decreased, but distribution density of CGRP-containing cells in medulla increased.
CONCLUSION
CGRP may affect function of the adrenal gland of burned rats.
目的
探讨烧伤后早期大鼠肾上腺髓质和皮质中降钙素基因相关肽（CGRP）的变化以及CGRP对烧伤大鼠肾上腺功能的影响。
方法
将大鼠随机分为两组：对照组和烧伤组。在烧伤后不同时间点测定肾上腺髓质中含CGRP神经纤维和细胞的分布密度。
结果
- 含CGRP神经纤维分布于被膜、皮质和髓质。肾上腺髓质中含CGRP神经纤维与CGRP免疫反应性细胞相关。2. 含CGRP神经纤维的分布密度降低，但髓质中含CGRP细胞的分布密度增加。
结论
CGRP可能影响烧伤大鼠的肾上腺功能。
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