Suppr超能文献

糖尿病患者的截肢手术:呼吁保留足部手术

Amputations in diabetic patients: a plea for footsparing surgery.

作者信息

Van Damme H, Rorive M, Martens De Noorthout B M, Quaniers J, Scheen A, Limet R

机构信息

Department of Cardiovascular Surgery, University Hospital of Liège, CHU du Sart-Tilman, Liège, Belgium.

出版信息

Acta Chir Belg. 2001 May-Jun;101(3):123-9.

Abstract

The authors observed a rather high rate of primary major amputation (above-knee or below-knee) performed for diabetic foot problems as well as an important revision rate for minor amputations (forefoot or toe) in diabetics. They reviewed their experience in order to compare it with more recent data from the literature, pleading for foot-sparing surgery. From 1993 to 1998, 186 amputations were performed on 146 diabetic patients. The cause of foot ulcers was neuropathy in 43 of them (51 episodes of diabetic foot problems) while in the remaining 103 patients (135 episodes of diabetic foot problems), diabetic macroangiopathy (absent ankle pulses) was on cause. For neuropathic foot problems, amputations were almost minor, resulting in a limb salvage rate of 90%. Only five of these patients (12%) had primary major limb amputation versus 43 of the dysvascular patients (42%). The reasons for major amputation by first intention were extensive tissue loss, intractable infection or non-reconstructible occlusive vessel disease, as judged by the surgeon. A foot-sparing surgery was attempted in 92 dysvascular cases. In only 44 of them, a preliminary vascular repair was performed. Twenty eight percent of the primary toe amputations and 24% of the forefoot amputations required secondary revision to a more proximal level. Minor amputations in case of diabetic neuropathy were characterized by a more favourable outcome: only 14% of the toe and 9% of the forefoot amputations failed. During follow-up, only 63% of the major amputations regained an autonomic walking capability with their prosthesis. Wound healing problems in diabetic foot are mainly due to infection and poor tissue perfusion. An aggressive control of the infection and distal revascularization of calf- or foot arteries, whenever possible, could improve the results of diabetic foot surgery. The poor functional recovery after major amputation (only 63% autonomic gait with limb prosthesis) argues for foot-sparing surgery whenever possible.

摘要

作者观察到,因糖尿病足问题进行的初次大截肢(膝上或膝下)比例相当高,糖尿病患者小截肢(前足或趾)的翻修率也很高。他们回顾了自身经验,以便与文献中的最新数据进行比较,主张采取保足手术。1993年至1998年期间,对146例糖尿病患者实施了186次截肢手术。其中43例(51次糖尿病足问题发作)足部溃疡的病因是神经病变,而其余103例患者(135次糖尿病足问题发作)的病因是糖尿病大血管病变(踝部脉搏消失)。对于神经性足部问题,截肢几乎都是小截肢,肢体挽救率为90%。这些患者中只有5例(12%)进行了初次大肢体截肢,而血管病变患者中有43例(42%)进行了初次大肢体截肢。根据外科医生的判断,一期大截肢的原因是广泛的组织损失、难以控制的感染或无法重建的闭塞性血管疾病。对92例血管病变病例尝试进行保足手术。其中只有44例进行了初步血管修复。28%的初次趾截肢和24%的前足截肢需要二次翻修至更高的部位。糖尿病神经病变患者的小截肢预后较好:只有14%的趾截肢和9%的前足截肢失败。在随访期间,只有63%的大截肢患者通过假肢恢复了自主行走能力。糖尿病足伤口愈合问题主要归因于感染和组织灌注不良。尽可能积极控制感染并对小腿或足部动脉进行远端血管重建,可能会改善糖尿病足手术的效果。大截肢后功能恢复不佳(只有63%的患者通过肢体假肢实现自主步态)表明应尽可能采取保足手术。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验