Pellacani G, Seidenari S
Department of Dermatology, University of Modena and Reggio Emilia, Italy.
Acta Derm Venereol. 2001 May;81(2):100-3. doi: 10.1080/00015550152384218.
Sorption-desorption and moisture accumulation tests are simple and quick methods for the in vivo functional analysis of stratum corneum hydration kinetics. The aim of this study was to evaluate the hydration dynamics of the uninvolved and affected skin of children with atopic dermatitis and to compare them with the skin of healthy children. The study investigated 45 children. The dynamic tests were performed using the corneometer CM820. Numerical parameters were calculated. With the sorption-desorption test, eczematous skin showed lower water accumulation during the sorption phase, whereas water was released more slowly during the desorption phase. With the moisture accumulation test, increases in water accumulation velocity and in water accumulation were observed in atopic children. Dynamic tests showed that the stratum corneum of unaffected atopic skin was less hydrated but more easily hydratable than normal skin. Conversely, despite a lower absorption capability, eczematous skin showed a greater avidity to retain water. New functional parameters (water-sorption capacity and accumulated water decay) are proposed to describe more precisely the hydration kinetics of eczematous skin.
吸附-解吸和水分累积测试是用于角质层水合动力学体内功能分析的简单快速方法。本研究的目的是评估特应性皮炎患儿未受累皮肤和受累皮肤的水合动力学，并将其与健康儿童的皮肤进行比较。该研究调查了45名儿童。使用角质层水合测定仪CM820进行动态测试。计算了数值参数。在吸附-解吸测试中，湿疹皮肤在吸附阶段的水分累积较低，而在解吸阶段水分释放较慢。在水分累积测试中，观察到特应性儿童的水分累积速度和水分累积量增加。动态测试表明，未受累的特应性皮肤的角质层水合程度低于正常皮肤，但比正常皮肤更容易水合。相反，尽管湿疹皮肤的吸收能力较低，但显示出更强的保水倾向。提出了新的功能参数（吸水能力和累积水分衰减）以更精确地描述湿疹皮肤的水合动力学。
