Szánthó A, Szabó I, Csapó Z S, Balega J, Demeter A, Papp Z
Department of Obstetrics and Gynecology, Semmelweis University, Faculty of Medicine, Budapest, Hungary.
Eur J Gynaecol Oncol. 2001;22(3):209-12.
The aim of this study was to determine the efficiency of transvaginal ultrasonography in the assessment of myometrial invasion and cervical involvement (preoperative staging) of endometrial cancer.
Transvaginal ultrasonography was performed on 52 women to classify endometrial cancer with respect to myometrial invasion and cervical involvement according to the International Federation of Gynaecologists and Obstetricians recommendations for surgical staging of endometrial cancer. Endometrial cancer was diagnosed on the basis of dilatation and curettage and the degree of invasion was evaluated preoperatively by transvaginal ultrasonography. Ultrasonographic findings were compared to the surgical staging and histopathology of the surgical specimen.
Myometrial invasion evaluated by transvaginal sonography was accurate in 46 of 52 cases (accuracy 88%, sensitivity 86%, specificity 90%, positive predictive value 92%, negative predictive value 83%). Tumor extension to the cervix was properly diagnosed in seven of ten women in which it was present.
Transvaginal ultrasonography is a reliable method for assessing myometrial invasion and cervical involvement. This non-invasive method should be included as an important tool in the establishment of individualized treatment programs for women with endometrial cancer.
本研究的目的是确定经阴道超声检查在评估子宫内膜癌肌层浸润和宫颈受累情况（术前分期）方面的有效性。
对52名女性进行经阴道超声检查，根据国际妇产科联合会关于子宫内膜癌手术分期的建议，对子宫内膜癌的肌层浸润和宫颈受累情况进行分类。根据刮宫诊断子宫内膜癌，并术前通过经阴道超声检查评估浸润程度。将超声检查结果与手术标本的手术分期和组织病理学结果进行比较。
经阴道超声评估的肌层浸润在52例中的46例中准确（准确率88%，敏感性86%，特异性90%，阳性预测值92%，阴性预测值83%）。在10名宫颈受累的女性中，有7名被正确诊断出肿瘤累及宫颈。
经阴道超声检查是评估肌层浸润和宫颈受累的可靠方法。这种非侵入性方法应作为为子宫内膜癌女性制定个体化治疗方案的重要工具。
