Szulc A, Galińska B, Konarzewska B, Gudel-Trochimowicz I, Popławska R
Klinika Chorób Psychicznych Akademii Medycznej w Białymstoku.
Pol Merkur Lekarski. 2001 Jun;10(60):450-2.
We evaluated immune-inflammatory markers in 32 first-episode schizophrenic patients during exacerbation of symptoms and during clinical improvement. Mean concentrations of sIL-2R and IFN-g was higher and mean concentration of sIL-6R was lower in cell cultures from blood of schizophrenic patients than in normal controls and there was no difference in IL-2 concentration. There was no correlation between concentrations of cytokines and demographic and clinical data. Our results may suggest that immune system disturbances could be observed in schizophrenia at the onset of the disease.
我们评估了32例首发精神分裂症患者在症状加重期和临床改善期的免疫炎症标志物。与正常对照组相比，精神分裂症患者血液细胞培养物中sIL-2R和IFN-γ的平均浓度较高，sIL-6R的平均浓度较低，而IL-2浓度无差异。细胞因子浓度与人口统计学和临床数据之间无相关性。我们的结果可能提示在精神分裂症发病时可观察到免疫系统紊乱。
