Diethelm L
Radiologe. 1979 Jul;19(7):245-53.
There is general agreement on the effectiveness of radiotherapy in the treatment of squamous cell carcinoma of the esophagus and the advantage of rotation technique with conventional as well as supervoltage therapy. The use of small fields in order to reduce the possibility of damage to neighbouring structures requires a more accurate positioning of the target than the use of large fields. In kilovoltage therapy this was guaranteed by controlling the field by fluoroscopy and by the possibility for correction during irradiation. This accuracy and possibility for correction is not yet reliably obtainable in supervoltage therapy as demonstrated by the number of complications reported. In the future, more fractionation, possibly using a higher initial dose, followed by hyperthermia, should be contemplated in order to reduce the total dose. The combination with chemotherapy deserves further development as well. For the treatment of operable tumors, preoperative irradiation with 2000-3000 rads immediately followed by resection is again recommended.
对于放射疗法治疗食管鳞状细胞癌的有效性以及旋转技术在传统放疗和超高压放疗中的优势,人们已达成普遍共识。为降低对邻近结构造成损伤的可能性而使用小照射野,相较于使用大照射野,需要对靶区进行更精确的定位。在千伏级放疗中,可通过荧光透视控制照射野以及在照射过程中进行校正来确保这一点。如所报告的并发症数量所示,在超高压放疗中尚未能可靠地获得这种精确性和校正可能性。未来,应考虑采用更多的分割方式,可能使用更高的初始剂量,随后进行热疗,以减少总剂量。与化疗联合也值得进一步研究。对于可手术切除的肿瘤,再次推荐先进行2000 - 3000拉德的术前放疗,然后立即进行手术切除。