Shephard R J, Franklin B
Faculty of Physical and Health Education, University of Toronto, Canada.
J Cardiopulm Rehabil. 2001 Jul-Aug;21(4):189-200. doi: 10.1097/00008483-200107000-00001.
Quality of life (QOL) is a major goal in the context of preventive and therapeutic cardiology. In this article, quality of life concepts are reviewed, factors limiting QOL in cardiac disease are identified, methods of measurement are explored, and clinically significant changes are defined. The changes effected by cardiac rehabilitation are considered, together with their physiological and psychological correlates. A final section suggests avenues for future research.
Relevant articles were identified by computer literature searches and review of extensive personal files.
In the past, there has been an excessive focus on extending the length rather than the quality of the cardiac patient's life. The overall QOL is a broad concept, influenced by personal perceptions, coping mechanisms, and environmental constraints. The ideal test instrument would be reliable, valid, and responsive to clinical change. Potential options include a Gestalt-type instrument, a disease-specific instrument, a function-specific instrument, or a detailed generic questionnaire. There have been relatively few comparisons between these potential approaches. Currently, the Standard Gamble (Gestalt-type), and Living With Heart Failure Questionnaire (disease-specific type), and the Medical Outcomes Study Short-Form 36 (SF-36) Health Survey (generic-type) are among the most popular approaches. Problems arise in distinguishing a clinically important from a statistically significant change; commonly a score change of 1 standard error of the mean is regarded as clinically important. Correlations of scores with clinical, physiological, and psychological change are sometimes weak, in part because of floor and ceiling effects. Nevertheless, potential gains in QOL provide a stronger argument for preventive and therapeutic programs than do increases in longevity.
The current literature supports the value of QOL measurements in the management of patients with cardiac disease. However, further research is needed to determine the optimum test instrument, and the best method of interpreting resultant scores.
生活质量(QOL)是预防和治疗心脏病领域的一个主要目标。本文回顾了生活质量的概念,确定了限制心脏病患者生活质量的因素,探讨了测量方法,并定义了具有临床意义的变化。同时考虑了心脏康复所带来的变化及其生理和心理关联。最后一部分提出了未来研究的方向。
通过计算机文献检索和查阅大量个人文档来确定相关文章。
过去,人们过度关注延长心脏病患者的生命长度而非质量。总体生活质量是一个宽泛的概念,受到个人认知、应对机制和环境限制的影响。理想的测试工具应可靠、有效且能对临床变化做出反应。潜在的选择包括整体型工具、疾病特异性工具、功能特异性工具或详细的通用问卷。这些潜在方法之间的比较相对较少。目前,标准博弈法(整体型)、《心力衰竭患者生活问卷》(疾病特异性型)和医疗结局研究简表36(SF - 36)健康调查(通用型)是最常用的方法。在区分具有临床重要性的变化和统计学上显著的变化时会出现问题;通常,平均得分变化1个标准差被视为具有临床重要性。得分与临床、生理和心理变化之间的相关性有时较弱,部分原因是存在地板效应和天花板效应。然而,生活质量的潜在提高为预防和治疗方案提供了比延长寿命更强有力的论据。
当前文献支持生活质量测量在心脏病患者管理中的价值。然而,需要进一步研究以确定最佳测试工具以及解释所得分数的最佳方法。