Rogiers X, Brunken C
Department of Hepatobiliary Surgery and Transplantation, Hamburg, Germany.
Saudi Med J. 2000 Jun;21(6):519-22.
In Europe, liver metastases are the most common malignomas of the liver. The majority of metastases are due to colorectal cancer. Radical surgical resection, if possible, is the treatment of choice. Radical resection of metastases from wilms-tumor, carcinoids, carcinoma of the breast, hypernephroma, adrenal tumors, malignant melanoma, leiomyosarcoma and gastric cancer may improve long time survival, however knowledge is too small for giving general directions. Local destructive therapies are only beneficial when a total necrosis of the tumor is reached. Indications for this treatment are quite rare. Both, systemic and local chemotherapy offers only palliation with little influence on long time survival. Adjuvant and neo-adjuvant chemotherapy is applicated under study conditions with encouraging results. Chemoembolisation of metastases might be useful in individual cases.
在欧洲，肝转移瘤是肝脏最常见的恶性肿瘤。大多数转移瘤是由结直肠癌引起的。如果可能的话，根治性手术切除是首选的治疗方法。对肾母细胞瘤、类癌、乳腺癌、肾上腺肿瘤、恶性黑色素瘤、平滑肌肉瘤和胃癌的转移瘤进行根治性切除可能会提高长期生存率，然而相关知识太少，无法给出一般性指导。局部毁损性治疗只有在肿瘤完全坏死时才有益处。这种治疗的适应证非常罕见。全身化疗和局部化疗都只能起到姑息作用，对长期生存影响很小。辅助化疗和新辅助化疗正在研究条件下应用，结果令人鼓舞。转移瘤的化疗栓塞在个别情况下可能有用。
