Ushiroyama T, Ikeda A, Ueki M
Department of Obstetrics and Gynecology, Osaka Medical College, Takatsuki, Japan.
J Med. 2000;31(5-6):311-9.
The present study evaluated the effects of clenbuterol and propiverine therapy on postmenopausal urinary incontinence. The patients consisted of 89 postmeopausal women with stress or urge incontinence who had consulted our out-patient clinic between March 1994 and February 1999. Patients were treated with either clenbuterol for stress incontinence or propiverine for urge incontinence. The administration period for both drugs was eight weeks. The cure rates for clenbuterol and propiverine were 41.2% and 52.6%, respectively. Both treatments significantly decreased the frequencies of incontinence, 24-h. voiding and nocturnal voiding, and both resulted in an overall clinical improvement. Furthermore, the two treatments resulted in significant subjective improvements in quality of life. We conclude that both medical treatments resulted in an improvement in urinary incontinence and contributed to overall quality of life. The present study demonstrated the necessity of contributed urinary incontinence with improvement in quality of life of postmenopausal women.
本研究评估了克仑特罗和丙哌维林治疗对绝经后尿失禁的影响。患者包括1994年3月至1999年2月间到我院门诊就诊的89名患有压力性或急迫性尿失禁的绝经后女性。压力性尿失禁患者用克仑特罗治疗，急迫性尿失禁患者用丙哌维林治疗。两种药物的给药期均为8周。克仑特罗和丙哌维林的治愈率分别为41.2%和52.6%。两种治疗均显著降低了尿失禁频率、24小时排尿次数和夜间排尿次数，且均使总体临床状况得到改善。此外，两种治疗均使生活质量得到显著的主观改善。我们得出结论，两种药物治疗均改善了尿失禁状况并提高了总体生活质量。本研究证明了改善绝经后女性生活质量对治疗尿失禁的必要性。
