散发性结直肠癌中微卫星不稳定性分级与错配修复通路靶基因之间的关系
Relationship between grade of microsatellite instability and target genes of mismatch repair pathways in sporadic colorectal carcinoma.
作者信息
Togo G, Shiratori Y, Okamoto M, Yamaji Y, Matsumura M, Sano T, Motojima T, Omata M
机构信息
Division of Gastroenterology, The Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan.
出版信息
Dig Dis Sci. 2001 Aug;46(8):1615-22. doi: 10.1023/a:1010628831884.
PMID:11508658
Abstract
Microsatellite instability (MSI) induces carcinoma through the alteration of target genes; TGF-beta RII, BAX, IGFIIR, hMSH3, and hMSH6. The grade of M
摘要
微卫星不稳定性（MSI）通过改变靶基因（转化生长因子-βⅡ型受体、BAX、胰岛素样生长因子Ⅱ受体、人错配修复蛋白3和人错配修复蛋白6）诱导癌症发生。MSI的分级…… （注：原文最后不完整）
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