Tsujimoto S, Arimura Y, Kuroda N, Kurehara H, Tashiro C
Department of Anesthesiology, Hyogo College of Medicine, Nishinomiya 663-8501.
Masui. 2001 Jul;50(7):799-804.
A newly developed non-invasive monitor, NICO (Novametrix Medical Systems Inc.), measures cardiac output based on changes in respiratory CO2 concentration caused by a brief period of rebreathing. By applying modified form of the CO2 Fick principle, cardiac output is calculated. We determined the accuracy and precision of this technique (RBCO) by comparing it with continuous thermodilution technique (TDCCO) and pulse dye densitometry technique (PDD). The overall difference between RBCO and TDCCO(n = 46) was -0.21 +/- 1.43 (bias +/- 2 SD)l.min-1. On the other hand, the overall difference between RBCO and PDD (n = 53) was -0.1 +/- 2.04 (bias +/- 2 SD)l.min-1. The degree of accuracy of RBCO was thought to be the same as those of TDCCO and PDD. We expect that NICO will be a useful cardiac output monitor in any method of general anesthesia in which PA catheterization is difficult or not indicated.
一种新开发的无创监测仪NICO（诺瓦梅克斯医疗系统公司），基于短暂重复呼吸引起的呼吸二氧化碳浓度变化来测量心输出量。通过应用二氧化碳菲克原理的改进形式来计算心输出量。我们通过将该技术（RBCO）与连续热稀释技术（TDCCO）和脉冲染料密度测定技术（PDD）进行比较，确定了该技术的准确性和精密度。RBCO与TDCCO（n = 46）之间的总体差异为-0.21±1.43（偏差±2标准差）升·分钟-1。另一方面，RBCO与PDD（n = 53）之间的总体差异为-0.1±2.04（偏差±2标准差）升·分钟-1。RBCO的准确度被认为与TDCCO和PDD相同。我们预计，在难以进行或不适合进行肺动脉导管插入术的任何全身麻醉方法中，NICO都将是一种有用的心输出量监测仪。
