Gritsenko S N, Sobokar' V A, Pisarenko I V, Voronoĭ A A, Veretennikov M V
Anesteziol Reanimatol. 2001 May-Jun(3):9-13.
The authors present the first clinical experience gained in anesthesia and intensive care during 8 orthotopic transplantations of the liver in 4 male and 4 female patients aged 24-50 years. Veno-venous bypass for general anesthesia is described. hemodynamic, oxygen balance, metabolic and blood clotting parameters during anesthesia and surgery are analyzed. Drastic changes were noted during the liver-free phase: oxygen delivery and consumption decreased almost twofold, a metabolic acidosis was observed before and, more so, during this phase.
作者介绍了在4名年龄在24至50岁之间的男性和4名女性患者进行8例原位肝移植手术期间,在麻醉和重症监护方面获得的首例临床经验。描述了用于全身麻醉的静脉-静脉旁路。分析了麻醉和手术期间的血流动力学、氧平衡、代谢和凝血参数。在无肝期观察到了剧烈变化:氧输送和消耗几乎下降了两倍,在此阶段之前以及此阶段期间观察到代谢性酸中毒,且在此阶段更为明显。