无静脉-静脉转流的原位肝移植

[Orthotopic liver transplantation with no veno-venous bypass].

作者信息

Zheng Shusen, Huang Dongsheng, Wu Jian, Wang Weilin, Shen Yan, Zhang Min, Shen Qingyun, Lu Anwei, Fu Peifen, Xu Xiao

机构信息

Department of Hepatobiliary Surgery, First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou 310003, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2002 May;40(5):326-8.

PMID:12133333

Abstract

OBJECTIVE

To assess the feasibility and outcome of orthotopic liver transplantation (OLT) with no veno-venous bypass (VVB) in adult patients.

METHODS

Between 1999 and June 2001, 43 adult patients were subjected to orthotopic liver transplantations with veno-venous bypass (28), or no veno-venous bypass (15).

RESULTS

There was no significant difference in mean serum creatinine on day 3 and gas discharge time in patients with veno-venous bypass or not. With no veno-venous bypass, the average operative time was 5.6 +/- 1.4 h, median amount of blood loss during operation was 4 200 +/- 850 ml, median amount of blood transfused intraoperatively was 4 800 +/- 920 ml, and median intensive care unit stay was 6.3 days. All these were lower or shorter than those of the patients with veno-venous bypass.

CONCLUSIONS

Orthotopic liver transplantation with no veno-venous bypass is safe and can be performed in the majority of adult patients. Liver transplantation with no veno-venous bypass is associated with shorter total operating time, lower blood product usage, and shorter intensive care unit stay compared with standard technique of OLT with routine use of VVB.

摘要

目的

评估成年患者不进行静脉-静脉转流（VVB）的原位肝移植（OLT）的可行性及结果。

方法

1999年至2001年6月期间，43例成年患者接受了原位肝移植，其中28例进行了静脉-静脉转流，15例未进行静脉-静脉转流。

结果

进行或未进行静脉-静脉转流的患者在术后第3天的平均血清肌酐水平及排气时间方面无显著差异。在不进行静脉-静脉转流的情况下，平均手术时间为5.6±1.4小时，术中失血量中位数为4200±850毫升，术中输血量中位数为4800±920毫升，重症监护病房停留时间中位数为6.3天。所有这些均低于或短于进行静脉-静脉转流的患者。