Zheng Shusen, Huang Dongsheng, Wu Jian, Wang Weilin, Shen Yan, Zhang Min, Shen Qingyun, Lu Anwei, Fu Peifen, Xu Xiao
Department of Hepatobiliary Surgery, First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou 310003, China.
Zhonghua Wai Ke Za Zhi. 2002 May;40(5):326-8.
To assess the feasibility and outcome of orthotopic liver transplantation (OLT) with no veno-venous bypass (VVB) in adult patients.
Between 1999 and June 2001, 43 adult patients were subjected to orthotopic liver transplantations with veno-venous bypass (28), or no veno-venous bypass (15).
There was no significant difference in mean serum creatinine on day 3 and gas discharge time in patients with veno-venous bypass or not. With no veno-venous bypass, the average operative time was 5.6 +/- 1.4 h, median amount of blood loss during operation was 4 200 +/- 850 ml, median amount of blood transfused intraoperatively was 4 800 +/- 920 ml, and median intensive care unit stay was 6.3 days. All these were lower or shorter than those of the patients with veno-venous bypass.
Orthotopic liver transplantation with no veno-venous bypass is safe and can be performed in the majority of adult patients. Liver transplantation with no veno-venous bypass is associated with shorter total operating time, lower blood product usage, and shorter intensive care unit stay compared with standard technique of OLT with routine use of VVB.
评估成年患者不进行静脉-静脉转流（VVB）的原位肝移植（OLT）的可行性及结果。
1999年至2001年6月期间，43例成年患者接受了原位肝移植，其中28例进行了静脉-静脉转流，15例未进行静脉-静脉转流。
进行或未进行静脉-静脉转流的患者在术后第3天的平均血清肌酐水平及排气时间方面无显著差异。在不进行静脉-静脉转流的情况下，平均手术时间为5.6±1.4小时，术中失血量中位数为4200±850毫升，术中输血量中位数为4800±920毫升，重症监护病房停留时间中位数为6.3天。所有这些均低于或短于进行静脉-静脉转流的患者。
不进行静脉-静脉转流的原位肝移植是安全的，且大多数成年患者均可进行。与常规使用VVB的标准OLT技术相比，不进行静脉-静脉转流的肝移植总手术时间更短，血制品使用量更低，重症监护病房停留时间更短。
