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鼻咽癌的放射治疗:治疗结果与优化标准(作者译)

[Radiation therapy of the nasopharyngeal carcinoma: results of treatment and criteria of optimization (author's transl)].

作者信息

Frommhold H, Leipner N, Herberhold C

出版信息

Strahlentherapie. 1979 Jul;155(7):441-50.

PMID:115118
Abstract

From 1968 till 1977, out of 84 patients with a malignoma of the nasopharynx 44 underwent sole radiation therapy with curative doses because of histologically established nasopharyngeal carcinoma. The 3-year survival rates for all the carcinomas amount to 63.2%, 5-year survival to 46.5%. Prognoses differ according to the histological type of carcinoma, but therapeutic results are also influenced by osseous involvement or by spread to the lymph nodes. Local recurrences appeared in 20% at the base of the skull, at the pharyngeal roof or in the region of the posterior nasal apertures. Following analysis of the patient collective a critical examination of imaginable and of practically used irradiation schedules is performed. Of the possible arrangements for radiation therapy those with readily reproducible parallel opposed field adjustments using ultrahard photon beams are to be preferred.

摘要

从1968年至1977年,84例鼻咽癌患者中,44例因组织学确诊为鼻咽癌而接受了根治性剂量的单纯放射治疗。所有癌症的3年生存率为63.2%,5年生存率为46.5%。预后因癌症的组织学类型而异,但治疗结果也受骨质受累或淋巴结转移的影响。20%的患者在颅底、咽顶或后鼻孔区域出现局部复发。在对患者群体进行分析后,对可想象的和实际使用的照射方案进行了批判性检查。在放射治疗的可能方案中,使用超硬光子束进行易于重复的平行相对野调整的方案更为可取。

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