van Andel J G
Radiol Clin (Basel). 1977;46(1):50-69.
80 patients with carcinoma of the nasopharynx classified according to TNM categories who have been treated in the RRTI between January 1947 and January 1966 are discussed. During 1947-1957 patients were treated by orthovoltage, and after this period by cobalt machine. The actuarial 5-year survival rate was 35%. Various factors such as age, sex, sign and symptoms, TNM classification, histology and type of treatment are discussed and related to the incidence of:local recurrence 27% (20/73); regional recurrence 29% (17/58); invasion of the base of the skull 21% (16/78); regional metastases 38% (30/78); distant metastases 49% (38/78), and to 5-year survival 33% (26/80). An overview is given of the present method of treatment in the RRTI based on the data in literature and obtained in this analysis.
本文讨论了1947年1月至1966年1月期间在皇家放射治疗研究所(RRTI)接受治疗的80例根据TNM分类的鼻咽癌患者。1947年至1957年期间,患者接受深部X线治疗,在此之后则采用钴治疗机治疗。精算5年生存率为35%。本文讨论了年龄、性别、体征和症状、TNM分类、组织学及治疗类型等各种因素,并分析了这些因素与以下情况发生率的关系:局部复发27%(20/73);区域复发29%(17/58);颅底侵犯21%(16/78);区域转移38%(30/78);远处转移49%(38/78),以及与5年生存率33%(26/80)的关系。基于文献数据及本分析所得结果,本文对皇家放射治疗研究所目前的治疗方法进行了概述。