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接受呼吸道感染性疾病干预(RRTI)治疗的鼻咽癌

Carcinoma of the nasopharynx treated in the RRTI.

作者信息

van Andel J G

出版信息

Radiol Clin (Basel). 1977;46(1):50-69.

PMID:830316
Abstract

80 patients with carcinoma of the nasopharynx classified according to TNM categories who have been treated in the RRTI between January 1947 and January 1966 are discussed. During 1947-1957 patients were treated by orthovoltage, and after this period by cobalt machine. The actuarial 5-year survival rate was 35%. Various factors such as age, sex, sign and symptoms, TNM classification, histology and type of treatment are discussed and related to the incidence of:local recurrence 27% (20/73); regional recurrence 29% (17/58); invasion of the base of the skull 21% (16/78); regional metastases 38% (30/78); distant metastases 49% (38/78), and to 5-year survival 33% (26/80). An overview is given of the present method of treatment in the RRTI based on the data in literature and obtained in this analysis.

摘要

本文讨论了1947年1月至1966年1月期间在皇家放射治疗研究所(RRTI)接受治疗的80例根据TNM分类的鼻咽癌患者。1947年至1957年期间,患者接受深部X线治疗,在此之后则采用钴治疗机治疗。精算5年生存率为35%。本文讨论了年龄、性别、体征和症状、TNM分类、组织学及治疗类型等各种因素,并分析了这些因素与以下情况发生率的关系:局部复发27%(20/73);区域复发29%(17/58);颅底侵犯21%(16/78);区域转移38%(30/78);远处转移49%(38/78),以及与5年生存率33%(26/80)的关系。基于文献数据及本分析所得结果,本文对皇家放射治疗研究所目前的治疗方法进行了概述。

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