肝素在不明原因胃肠道出血检查中的应用。
Use of heparin in the investigation of obscure gastrointestinal bleeding.
作者信息
Mernagh J R, O'Donovan N, Somers S, Gill G, Sridhar S
机构信息
Department of Radiology, McMaster University Medical Centre, 1200 Main St. W, Hamilton, ON L8N 3Z5.
出版信息
Can Assoc Radiol J. 2001 Aug;52(4):232-5.
OBJECTIVE
To determine if the administration of heparin improves the predictive value of angiography in the investigation of obscure gastrointestinal (GI) bleeding.
METHODS
18 patients with a history of chronic GI bleeding were investigated with angiography. For 6 patients, the cause of GI bleeding was established with angiography; the 12 patients who had negative results were given heparin for 24 h and were reassessed with angiography.
RESULTS
After heparin administration, the source of GI bleeding was determined with angiography for 6 of the remaining 12 patients. Thus, heparinization increased diagnostic yield from 33% (6 of 18) to 67% (12 of 18). No significant complications, such as uncontrolled GI bleeding, occurred.
CONCLUSION
Heparinization improves the diagnostic yield of angiography when obscure GI bleeding is being investigated.
目的
确定肝素的使用是否能提高血管造影在不明原因胃肠道（GI）出血检查中的预测价值。
方法
对18例有慢性GI出血病史的患者进行血管造影检查。6例患者通过血管造影确定了GI出血原因；对12例检查结果为阴性的患者给予肝素治疗24小时，然后再次进行血管造影重新评估。
结果
给予肝素后，其余12例患者中有6例通过血管造影确定了GI出血来源。因此，肝素化使诊断率从33%（18例中的6例）提高到67%（18例中的12例）。未发生明显并发症，如无法控制的GI出血。
结论
在对不明原因GI出血进行检查时，肝素化可提高血管造影的诊断率。
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