Jain T P, Gulati M S, Makharia G K, Bandhu S, Garg P K
Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Clin Radiol. 2007 Jul;62(7):660-7. doi: 10.1016/j.crad.2007.01.026. Epub 2007 May 11.
To evaluate the usefulness of computed tomography (CT) enteroclysis in patients with obscure gastrointestinal (GI) bleeding.
In a prospective study, CT enteroclysis was performed in 21 patients (median age 50 years; range 13-71 years) with obscure GI bleeding in which the source of the bleeding could not be detected despite the patient having undergone both upper GI endoscopic and colonoscopic examinations. The entire abdomen and pelvis was examined in the arterial and venous phases using multisection CT after distending the small intestine with 2l of 0.5% methylcellulose as a neutral enteral contrast medium and the administration of 150ml intravenous contrast medium.
Adequate distension of the small intestine was achieved in 20 of the 21 (95.2%) patients. Potential causes of GI bleeding were identified in 10 of the 21 (47.6%) patients using CT enteroclysis. The cause of the bleeding could be detected nine of 14 (64.3%) patients with overt, obscure GI bleeding. However, for patients with occult, obscure GI bleeding, the cause of the bleeding was identified in only one of the seven (14.3%) patients. The lesions identified by CT enteroclysis included small bowel tumours (n=2), small bowel intussusceptions (n=2), intestinal tuberculosis (n=2), and vascular lesions (n=3). All vascular lesions were seen equally well in both the arterial and venous phases.
The success rate in detection of the cause of bleeding using CT enteroclysis was 47.6% in patients with obscure GI bleeding. The diagnostic yield was higher in patients with overt, obscure GI bleeding than in those with occult obscure GI bleeding.
评估计算机断层扫描(CT)小肠造影在不明原因胃肠道(GI)出血患者中的应用价值。
在一项前瞻性研究中,对21例不明原因GI出血患者(中位年龄50岁;范围13 - 71岁)进行CT小肠造影检查,这些患者尽管已接受上消化道内镜检查和结肠镜检查,但仍未检测到出血源。使用2升0.5%甲基纤维素作为中性肠内造影剂扩张小肠,并静脉注射150毫升造影剂后,采用多层CT在动脉期和静脉期对整个腹部和盆腔进行检查。
21例患者中有20例(95.2%)小肠得到充分扩张。使用CT小肠造影在21例患者中的10例(47.6%)中发现了GI出血的潜在原因。在14例显性不明原因GI出血患者中的9例(64.3%)中检测到了出血原因。然而,对于隐匿性不明原因GI出血患者,在7例患者中仅1例(14.3%)确定了出血原因。CT小肠造影发现的病变包括小肠肿瘤(n = 2)、小肠套叠(n = 2)、肠结核(n = 2)和血管病变(n = 3)。所有血管病变在动脉期和静脉期显示效果相同。
CT小肠造影对不明原因GI出血患者出血原因的检出成功率为47.6%。显性不明原因GI出血患者的诊断率高于隐匿性不明原因GI出血患者。