Smith H R, Idris A H, Yokoyama W M
Howard Hughes Medical Institute, Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Immunol Rev. 2001 Jun;181:115-25. doi: 10.1034/j.1600-065x.2001.1810109.x.
Natural killer (NK) cells express two types of receptors involved in target recognition: inhibitory receptors for target cell MHC class I molecules and activation receptors. While there has been significant progress in understanding the inhibitory receptors, less is known about the activation receptors. Detailed analysis of several mouse NK-cell activation receptors provides insight into the physiologic relevance of these receptors in the innate immune response.
自然杀伤（NK）细胞表达两种参与靶细胞识别的受体：靶细胞MHC I类分子的抑制性受体和激活受体。虽然在理解抑制性受体方面取得了重大进展，但对激活受体的了解较少。对几种小鼠NK细胞激活受体的详细分析为这些受体在先天免疫反应中的生理相关性提供了深入见解。
