Silva F A, Borges F, Ferreira M A
Instituto Superior de Ciências da Saúde - Norte, Rua Central da Gandra 1317, Gandra, 4580 Paredes, Portugal.
J Agric Food Chem. 2001 Aug;49(8):3936-41. doi: 10.1021/jf010193p.
The oxidative stability of refined sunflower oil in the presence and in the absence of propyl caffeate (PC), propyl hydrocaffeate (PHC), propyl ferulate (PF), and propyl isoferulate (PI) has been evaluated according to the Rancimat method. The antioxidant activity of the phenolic derivatives was compared with that obtained with native [alpha-tocopherol (alpha-TOH)] and synthetic [propyl gallate (PG)] antioxidants. The results allow the establishment of a decreasing order of antioxidant power: PG > PHC > PC >> alpha-TOH > PI > PF. The oxidative stability was improved neither by the addition of PF nor by a supplement of alpha-TOH. Moreover, a positive antioxidant effect was obtained for PC that was placed between those of alpha-TOH and PG. The antioxidant activity of PHC was higher than that of its analogue (PC). A dose-dependent effect was observed for PG, PHC, and PC. A chain-breaking mechanism was proposed for the antioxidant activity of propyl phenolic esters because the same ranking order of efficacy was obtained for their antiradical activities evaluated by using the 2,2-diphenyl-1-picrylhydrazyl radical method.
根据Rancimat方法评估了精制葵花籽油在存在和不存在咖啡酸丙酯（PC）、氢化咖啡酸丙酯（PHC）、阿魏酸丙酯（PF）和异阿魏酸丙酯（PI）的情况下的氧化稳定性。将酚类衍生物的抗氧化活性与天然抗氧化剂[α-生育酚（α-TOH）]和合成抗氧化剂[没食子酸丙酯（PG）]的抗氧化活性进行了比较。结果确定了抗氧化能力的递减顺序：PG > PHC > PC >> α-TOH > PI > PF。添加PF或补充α-TOH均未提高氧化稳定性。此外，PC的抗氧化效果呈阳性，其抗氧化效果介于α-TOH和PG之间。PHC的抗氧化活性高于其类似物（PC）。观察到PG、PHC和PC具有剂量依赖性效应。由于通过2,2-二苯基-1-苦基肼自由基法评估的丙基酚酯的抗自由基活性获得了相同的功效排序，因此提出了丙基酚酯抗氧化活性的链断裂机制。
