Ronayne de Ferrer P A, Weisstaub A, López N, Ceriani Cernadas J M
Universidad de Buenos Aires, Hospital Italiano, Buenos Aires, Argentina.
Arch Latinoam Nutr. 2001 Mar;51(1):33-6.
Zinc is an essential element, important for early growth and development, and immune competence, which deficiency might be especially critical in preterm infants. Since published data have shown that some preterm milks have abnormally low zinc values, we decided to measure zinc levels in term and preterm milk, in order to assess if they were within normal values and if there were differences between both groups. Samples from 24 preterm and 20 term mothers (mean gestational age, 30.9 + 0.5 and 39.5 + 0.2 weeks, respectively) were collected and kept at -20 degrees C until analyzed by atomic absorption spectrophotometry, prior wet ashing with nitric acid. Both term and preterm milk showed zinc values within normal levels. No significant differences were registered between them. A decreasing trend was observed along time, which was significant between colostrum and mature milk samples (ANOVA, p < 0.05). In the term group, zinc concentrations in colostrum and mature milk (microgram/mL) (mean +/- SEM) varied between 6.96 +/- 0.69 y 2.44 +/- 0.11, while in the preterm group the values were 6.20 +/- 0.89 y 2.28 +/- 0.54. According to our results, zinc values in human milk were comparable between preterm and term mothers.
锌是一种必需元素,对早期生长发育和免疫能力很重要,其缺乏在早产儿中可能尤为关键。由于已发表的数据表明一些早产奶粉的锌含量异常低,我们决定测量足月儿和早产儿母乳中的锌水平,以评估其是否在正常范围内以及两组之间是否存在差异。收集了24名早产母亲和20名足月母亲的样本(平均孕周分别为30.9±0.5周和39.5±0.2周),并保存在-20℃,直到用硝酸进行湿式灰化后通过原子吸收分光光度法进行分析。足月儿和早产儿母乳的锌含量均在正常水平。两组之间未发现显著差异。随着时间的推移观察到一种下降趋势,初乳和成熟乳样本之间差异显著(方差分析,p<0.05)。在足月组中,初乳和成熟乳中的锌浓度(微克/毫升)(平均值±标准误)在6.96±0.69和2.44±0.11之间变化,而在早产组中,这些值分别为6.20±0.89和2.28±0.54。根据我们的结果,早产儿和足月儿母亲母乳中的锌含量具有可比性。