el Omri H, Sriha B, Kraiem I, Youssef Y B, Skouri H, Korbi S, Ennabli S
Service d'Hématologie Clinique, CHU Farhat Hached de Sousse.
Tunis Med. 2001 Apr;79(4):253-6.
Second malignant neoplasms are a major cause of late morbidity and mortality following treatment for Hodgkin's disease. Gastric carcinoma belong to the rare secondary malignancies induced by radiation-therapy and it is associated with a poor prognosis. We report a patient treated for Hodgkin's disease by 6 ABVD and total lymphoid radiation therapy, who developed a gastric carcinoma 9 years after completing treatment. Our case fits the criteria for radiation induced malignancies reported from the literature:
recommendations are presented for both prevention and early detection of the tumours we recommend a strict follow-up for patients treated for HD to detect second cancers.
第二原发性恶性肿瘤是霍奇金病治疗后晚期发病和死亡的主要原因。胃癌属于放疗诱发的罕见继发性恶性肿瘤,且预后较差。我们报告一例接受6周期ABVD方案化疗及全淋巴放疗的霍奇金病患者,在完成治疗9年后发生了胃癌。我们的病例符合文献报道的放疗诱发恶性肿瘤的标准:
提出了针对此类肿瘤的预防和早期检测的建议,我们建议对接受霍奇金病治疗的患者进行严格随访以检测第二癌症。