Powers L J, Dillingham E O, Bass G E
J Pharm Sci. 1975 May;64(5):883-5. doi: 10.1002/jps.2600640540.
Fifteen aliphatic diamines substituted with one long alkyl chain (C10-C18), a varying number of methylene groups separating the nitrogens (two to six), and various aliphatic substituents were synthesized and their CMC's were determined. While the length of the long alkyl chain plays a dominant role in influencing the CMC, the other N-alkyl substituents as well as the length of the methylene chain separating the two nitrogens of the diamine are significant factors.
合成了15种脂肪族二胺,它们被一个长烷基链(C10 - C18)取代,氮原子之间间隔不同数量的亚甲基(2至6个),并且带有各种脂肪族取代基,同时测定了它们的临界胶束浓度(CMC)。虽然长烷基链的长度在影响临界胶束浓度方面起主导作用,但其他N - 烷基取代基以及二胺中分隔两个氮原子的亚甲基链的长度也是重要因素。