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海蕴提取物的抗炎机制

Anti-inflammation mechanism of extract from Eisenia bicyclis (Kjellman) Setchell.

作者信息

Whitaker D M, Carlson G P

出版信息

J Pharm Sci. 1975 Jul;64(7):1258-9. doi: 10.1002/jps.2600640735.

DOI:10.1002/jps.2600640735
PMID:1151693
Abstract

An extract from Eisenia bicyclis, previously shown to possess anti-inflammatory activity, was found to stabilize lysosomal membranes in vitro as determined by measurement of inhibition of the marker enzyme beta-glucuronidase. Some anti-inflammatory activity was also due to counterirritancy.

摘要

先前已证明具有抗炎活性的海带提取物,通过测量标记酶β-葡萄糖醛酸酶的抑制作用来确定,在体外可稳定溶酶体膜。一些抗炎活性也归因于抗刺激作用。

相似文献

1
Anti-inflammation mechanism of extract from Eisenia bicyclis (Kjellman) Setchell.海蕴提取物的抗炎机制
J Pharm Sci. 1975 Jul;64(7):1258-9. doi: 10.1002/jps.2600640735.
2
Lysosomal stabilization as the possible mechanism of action of an endogenous anti-inflammatory protein.溶酶体稳定化作为一种内源性抗炎蛋白可能的作用机制。
Biochem Pharmacol. 1976 Sep 15;25(18):2039-44. doi: 10.1016/0006-2952(76)90427-5.
3
Stabilization of rat liver lysosomes by new anti-inflammatory steroids in vitro.新型抗炎甾体在体外对大鼠肝脏溶酶体的稳定作用
Steroids. 1981 Oct;38(4):365-73. doi: 10.1016/0039-128x(81)90071-4.
4
Effects of anti-inflammatory drugs on the stability of rat liver lysosomes in vitro.抗炎药物对大鼠肝溶酶体体外稳定性的影响。
Biochem Pharmacol. 1971 Oct;20(10):2847-60. doi: 10.1016/0006-2952(71)90196-1.
5
Effects of fenbufen and other anti-inflammatory drugs on rat liver lysosomes.
Biochem Pharmacol. 1976 Oct 15;25(20):2303-7. doi: 10.1016/0006-2952(76)90014-9.
6
Effect of anti-inflammatory drugs on lysosomes and lysosomal enzymes from rat liver.
Biochem Pharmacol. 1976 Oct 1;25(19):2171-7. doi: 10.1016/0006-2952(76)90129-5.
7
Dissimilar effects of anti-inflammatory drugs on stability of lysosomes from peritoneal and circulating leukocytes and liver.抗炎药物对腹膜和循环白细胞以及肝脏溶酶体稳定性的不同影响。
Biochem Pharmacol. 1971 Oct;20(10):2861-70. doi: 10.1016/0006-2952(71)90197-3.
8
[Studies on anti-inflammatory agents. X. Stabilization of rat liver lysosome by 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno [2,3-c]pyridine (Y-3642)].[抗炎剂的研究。X. 2-氨基-3-乙氧羰基-6-苄基-4,5,6,7-四氢噻吩并[2,3-c]吡啶(Y-3642)对大鼠肝脏溶酶体的稳定作用]
Yakugaku Zasshi. 1970 May;90(5):557-63. doi: 10.1248/yakushi1947.90.5_557.
9
Preservation of structural integrity of liver lysosomes and membrane-stabilizing action of anti-inflammatory drugs, catecholamines and cyclic adenosine monophosphate in isotonic salt media.
Biochem Pharmacol. 1973 Jun 1;22(11):1269-82. doi: 10.1016/0006-2952(73)90301-8.
10
Influence of butibufen on enzyme activity and lysosomal stabilization ex vivo: a comparative study with hydrocortisone and acetylsalicylic acid.布替布芬对离体酶活性和溶酶体稳定性的影响:与氢化可的松和乙酰水杨酸的比较研究
Methods Find Exp Clin Pharmacol. 1995 Jun;17(5):303-10.

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Extract Inhibits α-MSH-Induced Melanogenesis in B16F10 Cells via Down-Regulation of CREB Signaling Pathway.
提取物通过下调 CREB 信号通路抑制 B16F10 细胞中的 α-MSH 诱导的黑色素生成。
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Edible seaweed, Eisenia bicyclis, protects retinal ganglion cells death caused by oxidative stress.可食用海藻,双齿围沙蚕,可保护氧化应激引起的视网膜神经节细胞死亡。
Mar Biotechnol (NY). 2012 Aug;14(4):383-95. doi: 10.1007/s10126-012-9459-y. Epub 2012 May 18.