Moskalyk R E, Locock R A, Chatten L G, Veltman A M, Bielech M F
J Pharm Sci. 1975 Aug;64(8):1406-8. doi: 10.1002/jps.2600640835.
A method is presented for the quantitative analysis of polythiazide tablets by high-pressure liquid chromatography. The powdered tablets are extracted with methanol, containing quinoline as the internal standard, and assayed by comparison of peak heights after liquid chromatography. The chromatographic conditions employed may be adapted for the determination of many other thiazide and nonthiazide diuretics.
本文介绍了一种用高压液相色谱法对多噻嗪片进行定量分析的方法。将片剂粉末用含有喹啉作为内标的甲醇提取，然后通过液相色谱后比较峰高进行测定。所采用的色谱条件可适用于许多其他噻嗪类和非噻嗪类利尿剂的测定。
