体外培养的胎鼠和新生大鼠肠道对糖的吸收
Sugar absorption by foetal and neonatal rat intestine in vitro.
作者信息
Bamford D R, Ingham P A
出版信息
J Physiol. 1975 Jun;248(2):335-48. doi: 10.1113/jphysiol.1975.sp010977.
Abstract
- Sugar absorption by foetal and neonatal rat intestine has been examined using an in vitro accumulation technique. 2. The capacity for active sugar absorption is present in the rat intestine by the 17th day of gestation. Considerable variation in uptake occurs during the first month post partum; the greatest uptake place during the first week. 3. The absorption of sugars by the developing gut resembles in several respects that by the mature intestine. However, the adult pattern of functional localization along the intestine is not fully established until after the 3rd week post partum. 4. Kinetic studies indicate that variations with age in the distribution of sugar "carriers' along the intestine, rather than changes in the "carriers' themselves, account for the observed variations in absorption.
摘要
- 已使用体外积累技术研究了胎儿和新生大鼠肠道对糖的吸收情况。2. 妊娠第17天时，大鼠肠道已具备主动吸收糖的能力。产后第一个月内，摄取量存在相当大的差异；摄取量最大的时候是在第一周。3. 发育中的肠道对糖的吸收在几个方面与成熟肠道相似。然而，直到产后第3周后，肠道沿肠段的功能定位的成年模式才完全建立。4. 动力学研究表明，肠道中糖“载体”分布随年龄的变化，而非“载体”本身的变化，是观察到的吸收差异的原因。
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