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胶原蛋白、人源胶原蛋白与脂肪:寻找一种三维软组织填充剂。

Collagen, human collagen, and fat: the search for a three-dimensional soft tissue filler.

作者信息

Sclafani A P, Romo T

机构信息

Division of Facial Plastic Surgery, The New York Eye and Ear Infirmary, 310 East 14th Street, New York, NY 10003, USA.

出版信息

Facial Plast Surg. 2001 Feb;17(1):79-85. doi: 10.1055/s-2001-16368.

DOI:10.1055/s-2001-16368
PMID:11518980
Abstract

As the body ages, not only are the soft tissues of the face subject to gravity but they also may undergo progressive atrophy. Suspensory procedures may return the tissues to a more youthful position, but the atrophic changes are left uncorrected and produce an aged appearance. Three-dimensional (3-D) soft tissue fillers ideally would replace the bulk that was lost. Safety, persistence, and verisimilitude to the native tissues should be optimal in useful 3-D fillers. To date, no such material has been described, but there has been a resurgence in natural materials for this purpose. This article serves as an update on human-derived soft tissue fillers.

摘要

随着身体衰老,面部软组织不仅会受到重力影响,还可能会逐渐萎缩。悬吊手术可以将组织恢复到更年轻的位置,但萎缩性变化仍未得到纠正,从而产生衰老的外观。理想情况下,三维(3-D)软组织填充剂可以替代流失的体积。对于有用的3-D填充剂,安全性、持久性以及与天然组织的相似性应达到最佳。迄今为止,尚未有此类材料的描述,但为此目的使用天然材料的情况有所复苏。本文是关于人源软组织填充剂的最新进展。

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