Agmo A
J Reprod Fertil. 1975 Jul;44(1):69-75. doi: 10.1530/jrf.0.0440069.
Cyproterone acetate (CA) was injected daily in eleven rabbits for 3 weeks at a dose of 20 mg/day, and for a further week at a dose of 40 mg/day. After 3 weeks of treatment, the ejaculation frequency was reduced but other measures of sexual behaviour were not significantly changed. There was no reduction in the fructose concentration of the semen, but the volume of the ejaculates decreased. The vesicular glands from the experimental animals showed histological changes typical of those occurring after castration. It was concluded that CA reduced the activity of at least one of the accessory sex glands as well as sexual behaviour. This lends support to the current hypothesis that the endocrine regulation of rabbit sexual behaviour differs from that of the rat.
对11只兔子每日注射醋酸环丙孕酮（CA），剂量为20毫克/天，持续3周，之后剂量增加到40毫克/天，再持续1周。治疗3周后，射精频率降低，但其他性行为指标无显著变化。精液中的果糖浓度没有降低，但射精量减少。实验动物的精囊出现了去势后典型的组织学变化。研究得出结论，醋酸环丙孕酮降低了至少一种附属性腺的活性以及性行为。这支持了当前的假设，即兔子性行为的内分泌调节与大鼠不同。
