Agmo A, Södersten P
J Endocrinol. 1975 Dec;67(3):327-32. doi: 10.1677/joe.0.0670327.
Sexual behaviour and the function of the accessory sexual glands were studied in castrated rabbits injected with testosterone benzoate (TB), oestradiol benzoate (OEB), dihydrotestosterone benzoate (DHTB) or OEB in combination with DHTB. Testosterone benzoate (1 mg daily for 90 days) stimulated the sexual behaviour more than any of the other steroids. The combination of OEB (0-33 mg) and DHTB (1 mg) was no more effective than either of these steroids given alone. The function of the accessory sexual glands was stimulated to a level comparable to that of intact animals given TB. Dihydrotestosterone benzoate was, however, not very effective in this respect. Oestradiol benzoate alone or in combination with DHTB caused hypertrophy and very low secretory activity of the seminal vesicles. These results suggest that testosterone itself is active both in the brain and in the accessory sexual glands in rabbits. This is in contrast to the rat, in which aromatization to oestradiol in the brain and reduction to DHT in the periphery seems to be important.
对注射了苯甲酸睾酮（TB）、苯甲酸雌二醇（OEB）、苯甲酸双氢睾酮（DHTB）或OEB与DHTB组合的去势兔的性行为和附属性腺功能进行了研究。苯甲酸睾酮（每天1毫克，共90天）比其他任何一种类固醇更能刺激性行为。OEB（0 - 33毫克）和DHTB（1毫克）的组合并不比单独给予这两种类固醇中的任何一种更有效。附属性腺的功能被刺激到与给予TB的完整动物相当的水平。然而，苯甲酸双氢睾酮在这方面不是很有效。单独使用苯甲酸雌二醇或与DHTB联合使用会导致精囊肥大且分泌活性非常低。这些结果表明，睾酮本身在兔的大脑和附属性腺中均具有活性。这与大鼠形成对比，在大鼠中，睾酮在大脑中芳香化为雌二醇以及在外周还原为双氢睾酮似乎很重要。
