Poiraudeau S, Chevalier X, Conrozier T, Flippo R M, Lioté F, Noël E, Lefevre-Colau M M, Fermanian J, Revel M, Rhumato R
The Réseau Rhumato Group, Paris, France.
Osteoarthritis Cartilage. 2001 Aug;9(6):570-7. doi: 10.1053/joca.2001.0422.
To assess the reliability, validity and sensitivity to change of the Cochin hand functional scale in hand osteoarthritis (OA).
The Cochin hand functional disability scale has been validated in rheumatoid arthritis.
Patients with hand OA according to Altman's criteria were included. Impairment outcome measures (VAS of pain, hand score of tenderness, clinical hand score of impairment, Kallman's radiographic scale), functional disability measures [Cochin scale, Revel's functional index (RFI), Dreiser's functional index (DFI)] and patients' perceived handicap (VAS) were recorded twice, at baseline and at a 6-month follow-up visit. Interobserver reliability was assessed using the intraclass correlation coefficient (ICC) and the Bland and Altman method. Construct (convergent and divergent) validity was investigated using the Spearman rank correlation coefficient and a factor analysis was performed. Sensitivity to change was assessed using the effect size (ES) and the standardized response mean (SRM), and the non-parametric Spearman rank correlation coefficient (r) was used to assess the correlation between quantitative variable changes and patient's overall opinion.
89 patients (8 males, mean age 63 years) were included. Interobserver reliability was excellent (ICC=0.96). The Bland and Altman method showed no systematic trend. Correlations of the Cochin scale score with RFI (r=0.86), DFI (r=0.87), VAS of handicap (r=0.67), VAS of pain (r=0.54), tenderness (r=0.51), clinical impairment (r=0.32), and Kallman's radiographic scale (r=0.13) indicated a good construct validity. Factor analysis extracted four main factors, accounting for 65% of the total variance. 51 patients were evaluated at the 6-month visit. The Cochin scale score had worsened with SRM and ES values of -0.26 and -0.17 respectively. Changes in the score had one of the highest correlation (r=0.47) with the patient's overall opinion.
The Cochin hand functional disability scale which was first developed to assess the rheumatoid hand can be used to evaluate functional disability in hand OA.
评估科钦手部功能量表在手部骨关节炎（OA）中的可靠性、有效性及对变化的敏感性。
科钦手部功能障碍量表已在类风湿关节炎中得到验证。
纳入符合阿尔特曼标准的手部OA患者。在基线和6个月随访时，记录损伤结局指标（疼痛视觉模拟评分、压痛手部评分、临床手部损伤评分、卡尔曼放射学量表）、功能障碍指标[科钦量表、雷韦尔功能指数（RFI）、德雷泽功能指数（DFI）]以及患者的感知障碍（视觉模拟评分）。采用组内相关系数（ICC）和布兰德-奥特曼方法评估观察者间信度。使用斯皮尔曼等级相关系数研究结构效度（收敛效度和区分效度）并进行因子分析。使用效应量（ES）和标准化反应均值（SRM）评估对变化的敏感性，非参数斯皮尔曼等级相关系数（r）用于评估定量变量变化与患者总体评价之间的相关性。
纳入89例患者（8例男性，平均年龄63岁）。观察者间信度极佳（ICC = 0.96）。布兰德-奥特曼方法未显示出系统趋势。科钦量表评分与RFI（r = 0.86）、DFI（r = 0.87）、障碍视觉模拟评分（r = 0.67）、疼痛视觉模拟评分（r = 0.54）、压痛（r = 0.51）、临床损伤（r = 0.32）及卡尔曼放射学量表（r = 0.13）的相关性表明其具有良好的结构效度。因子分析提取出四个主要因子，占总方差的65%。51例患者在6个月随访时接受评估。科钦量表评分恶化，SRM和ES值分别为 - 0.26和 - 0.17。评分变化与患者总体评价的相关性最高（r = 0.47）之一。
最初用于评估类风湿手部的科钦手部功能障碍量表可用于评估手部OA的功能障碍。
