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5'-羧基乙酯腺苷对心脏和冠脉循环的影响。

Effects of ethyl adenosine-5'-carboxylate on the heart and coronary circulation.

作者信息

Imai S, Otorii T, Takeda K, Katano Y, Horii D

出版信息

Jpn Heart J. 1975 Jul;16(4):421-32. doi: 10.1536/ihj.16.421.

DOI:10.1536/ihj.16.421
PMID:1152296
Abstract

Using the canine heart-lung preparation supported by a donor, the effects of ehtyl adenosine-5'-carboxylate (EAC) on the heart and coronary circulation were studied and compared with those of adenosine. EAC produced qualitatively similar effects to adenosine in this preparation. Aminophylline inhibited the effects of EAC as well as those of adenosine. Dipyridamole did not potentiate the effects of EAC, while it produced a definite potentiation of the effects of adenosine.

摘要

利用由供体支持的犬心肺制备模型，研究了5'-羧基乙基腺苷（EAC）对心脏和冠状动脉循环的影响，并与腺苷的影响进行了比较。在该制备模型中，EAC产生了与腺苷在性质上相似的作用。氨茶碱抑制了EAC以及腺苷的作用。双嘧达莫没有增强EAC的作用，而它对腺苷的作用有明显的增强作用。

相似文献

1
Effects of ethyl adenosine-5'-carboxylate on the heart and coronary circulation.5'-羧基乙酯腺苷对心脏和冠脉循环的影响。
Jpn Heart J. 1975 Jul;16(4):421-32. doi: 10.1536/ihj.16.421.
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Systemic and coronary hemodynamic effects of Abbott (40557) and its interaction with aminophylline.雅培（40557）的全身和冠状动脉血流动力学效应及其与氨茶碱的相互作用。
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Inter-relations between the actions of dipyridamole, adenosine, aminophylline and propranolol on the coronary circulation of the transplanted dog heart.潘生丁、腺苷、氨茶碱及普萘洛尔对移植犬心脏冠脉循环作用之间的相互关系。
Aust J Exp Biol Med Sci. 1971 Dec;49(6):537-52. doi: 10.1038/icb.1971.60.
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The effect of dipyridamole and of aminophyline on responses to sixty-second coronary artery occlusions in dogs.双嘧达莫和氨茶碱对犬60秒冠状动脉闭塞反应的影响。
Aust J Exp Biol Med Sci. 1973 Oct;51(5):631-42. doi: 10.1038/icb.1973.59.
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Systemic and coronary hemodynamic effects of hexobendine and its interaction with adenosine and aminophylline.己酮可可碱的全身和冠状动脉血流动力学效应及其与腺苷和氨茶碱的相互作用。
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The potentiation of the activity of adenosine on coronary blood flow, blood pressure and heart rate by inosine in the dog.肌苷对犬腺苷在冠状动脉血流量、血压及心率方面活性的增强作用。
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