Lamerz R, Fateh-Moghadam A
Klin Wochenschr. 1975 May 1;53(9):403-17. doi: 10.1007/BF01493365.
The occurrance and significance of important carcinofetal antigens other than AFP and CEA are reported. These included the alpha 2 H-protein which is produced in the liver and increases in serum of patients with various tumors, the fetal sulphoglycoprotein antigen FSA from the gastric juice of patients with gastric cancer, the carcinoplacental alkaline phosphatase (REGAN-isoenzyme)which is found in the serum of patients suffering from e.g. bronchogenic, mammary, urogenital and gastrointestinal carcinomas, the beta-S-fetoprotein which is most likely to be identical with C-reactive protein, gamma-fetoprotein, the carcinofetal antigen in glial tumors (CFGA); ectopic production of placental hormones like human gonadotropin, placental lactogen, plasminogen-activators; leukemia-associated antigens. Furthermore, some other less known carcinofetal antigens are mentioned.
本文报道了除甲胎蛋白（AFP）和癌胚抗原（CEA）之外的重要癌胚抗原的发生情况及其意义。这些抗原包括在肝脏中产生且在各种肿瘤患者血清中含量增加的α2H蛋白、来自胃癌患者胃液的胎儿硫糖蛋白抗原FSA、在例如支气管癌、乳腺癌、泌尿生殖系统癌和胃肠道癌患者血清中发现的癌胎盘碱性磷酸酶（REGAN同工酶）、极有可能与C反应蛋白相同的β-S-胎蛋白、γ-胎蛋白、神经胶质瘤中的癌胚抗原（CFGA）；胎盘激素如人绒毛膜促性腺激素、胎盘催乳素、纤溶酶原激活剂的异位产生；白血病相关抗原。此外，还提到了一些其他鲜为人知的癌胚抗原。
