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炎症性泄殖腔源性息肉中发生的原位鳞状细胞癌:两例HPV DNA的PCR分析报告

Squamous cell carcinoma in situ arising in inflammatory cloacogenic polyps: report of two cases with PCR analysis for HPV DNA.

作者信息

Jaworski R C, Biankin S A, Baird P J

机构信息

Department of Tissue Pathology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, New South Wales, Australia.

出版信息

Pathology. 2001 Aug;33(3):312-4.

PMID:11523931
Abstract

Inflammatory cloacogenic polyp (ICP) is regarded as part of the spectrum of pathological changes encountered in mucosal prolapse syndrome (MPS)/solitary rectal ulcer. We present the clinicopathological features of two females with squamous cell carcinoma in situ arising in their ICPs. Human papillomavirus (HPV) type 16 was demonstrated in the areas of squamous carcinoma in situ in both polyps by polymerase chain reaction. These cases highlight the need for close scrutiny of the squamous components of these lesions.

摘要

炎性泄殖腔源性息肉(ICP)被视为黏膜脱垂综合征(MPS)/孤立性直肠溃疡中所遇到的一系列病理变化的一部分。我们报告了两例女性患者的临床病理特征,她们的ICP中发生了原位鳞状细胞癌。通过聚合酶链反应在两个息肉的原位鳞状癌区域检测到16型人乳头瘤病毒(HPV)。这些病例强调了对这些病变的鳞状成分进行仔细检查的必要性。

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