直肠中段鳞状细胞癌：1例报告及文献综述
Squamous cell carcinoma of the middle rectum: Report of a case and literature overview.
作者信息
Scaringi Stefano, Bisogni Damiano, Messerini Luca, Bechi Paolo
机构信息
Second General Surgery, Department of Surgery and Translational Medicine, Careggi Teaching Hospital, Florence, Italy.
Second General Surgery, Department of Surgery and Translational Medicine, Careggi Teaching Hospital, Florence, Italy.
出版信息
Int J Surg Case Rep. 2015;7C:127-9. doi: 10.1016/j.ijscr.2014.10.097. Epub 2014 Nov 5.
INTRODUCTION
Squamous-cell carcinoma (SCC) of the middle rectum is a rare disease with an estimated incidence of 0.1-0.25/1000 colorectal neoplasms. Literature is represented essentially by case report and short series, and only seventy-six cases of colorectal squamous carcinoma have been documented in literature.
PRESENTATION OF CASE
We report the case of a SCC of the middle rectum, associated to an ureteral inverted papilloma, occurred in a patient with a past history of prostate cancer treated with prostatectomy and radiotherapy.
DISCUSSION
Colorectal squamous-cell carcinoma is a rare disease. This localization is more frequent than the right colon, but no more epidemiological informations are actually available apart from a slight predominance of the female sex. Risk factors for SCC of the rectum are unknown and many hypotheses have been evocated. Because of its rarity, the interpretation of available information is clouded by a lack of uniformity in diagnosis and treatment.
CONCLUSION
Treatment of SCC remains very challenging, and the acquisition of more consistent data is needed.
引言
直肠中段鳞状细胞癌是一种罕见疾病，估计发病率为每1000例结直肠肿瘤中有0.1 - 0.25例。文献主要以病例报告和短篇系列为主，文献中仅记载了76例结直肠鳞状细胞癌。
病例介绍
我们报告一例直肠中段鳞状细胞癌病例，该病例与输尿管内翻乳头状瘤相关，患者有前列腺癌病史，曾接受前列腺切除术和放疗。
讨论
结直肠鳞状细胞癌是一种罕见疾病。这种定位比右半结肠更常见，但除了女性略有优势外，目前没有更多的流行病学信息。直肠鳞状细胞癌的危险因素尚不清楚，人们提出了许多假说。由于其罕见性，现有信息的解读因诊断和治疗缺乏一致性而受到影响。
结论
鳞状细胞癌的治疗仍然极具挑战性，需要获取更一致的数据。
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