Scurry J, Kerdemelidis P, Fortune D
Mercy Pathology, Mercy Hospital for Women, Melbourne, Victoria, Australia.
Pathology. 2001 Aug;33(3):319-21.
We describe two small atypical leiomyomas. The first was a 6-mm de novo lesion in a 53-year-old woman. The second was a 3-mm focus in a 12-mm leiomyoma in a 45-year-old woman. Both lesions showed moderate atypia and a mitotic rate of six per 10 high-power fields. Coagulative necrosis was not seen. Neither patient had received exogenous oestrogen or progestogen. There was no evidence of recurrence or metastasis in either patient after 60 months of follow-up. Our report provides evidence that atypical uterine leiomyomas may arise either de novo or within a leiomyoma.
我们描述了两例小的非典型平滑肌瘤。第一例是一名53岁女性的6毫米新发病灶。第二例是一名45岁女性12毫米平滑肌瘤中的3毫米病灶。两个病灶均显示中度异型性，每10个高倍视野有6个核分裂象。未见凝固性坏死。两名患者均未接受过外源性雌激素或孕激素治疗。随访60个月后，两名患者均无复发或转移迹象。我们的报告提供了证据，表明非典型子宫平滑肌瘤可能新发或在平滑肌瘤内发生。
