Finnie J W, Blumbergs P C, Manavis J, Utteridge T D, Gebski V, Swift J G, Vernon-Roberts B, Kuchel T R
Veterinary Services Division, Institute of Medical and Veterinary Science, Adelaide, SA, Australia.
Pathology. 2001 Aug;33(3):338-40.
The effect of global system for mobile communication (GSM) radiofrequency fields on vascular permeability in the brain was studied using a purpose-designed exposure system at 898.4 MHz. Mice (n= 30) were given a single far field, whole body exposure for 60 minutes at a specific absorption rate of 4 W/kg. Control mice were also sham-exposed (n = 10) or permitted free movement in a cage (n = 10) to exclude any stress-related effects. Vascular permeability changes were detected using albumin immunohistochemistry and the efficacy of this vascular tracer was confirmed with a positive control group exposed to a clostridial toxin known to increase vascular permeability in the brain. No significant difference in albumin extravasation was detected between any of the groups at the light microscope level using the albumin marker.
利用专门设计的暴露系统，在898.4兆赫兹频率下研究了全球移动通信系统（GSM）射频场对脑内血管通透性的影响。30只小鼠接受了单次远场全身暴露，比吸收率为4瓦/千克，暴露时长60分钟。对照小鼠也接受了假暴露（n = 10）或被允许在笼中自由活动（n = 10），以排除任何与应激相关的影响。使用白蛋白免疫组织化学检测血管通透性变化，并用暴露于已知可增加脑内血管通透性的梭菌毒素的阳性对照组证实了这种血管示踪剂的有效性。在光学显微镜水平上，使用白蛋白标记物未检测到任何组之间白蛋白外渗有显著差异。
