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婚姻质量对充血性心力衰竭患者生存的预后重要性。

Prognostic importance of marital quality for survival of congestive heart failure.

作者信息

Coyne J C, Rohrbaugh M J, Shoham V, Sonnega J S, Nicklas J M, Cranford J A

机构信息

Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4283, USA.

出版信息

Am J Cardiol. 2001 Sep 1;88(5):526-9. doi: 10.1016/s0002-9149(01)01731-3.

Abstract

Mounting evidence indicates that social support is associated with better outcomes of cardiovascular disease and reduced all-cause mortality. Much less is known about the specific contribution of marital functioning to these outcomes, and the potential prognostic significance of marital quality for congestive heart failure (CHF) has not been explored. Interview and observational measures of marital quality obtained from 189 patients with CHF (139 men and 50 women) and their spouses were examined as predictors of patient survival up to 48 months after assessment and compared with prediction based on illness severity (New York Heart Association [NYHA] class). Four-year survival rates were 52.5% and 68% for male patients and female patients, respectively. In Cox regression analyses, a composite measure of marital quality predicted 4-year survival as well as the patient's concurrent NYHA class did (both p <0.001). Adjusting for CHF severity did not diminish the prognostic significance of marital functioning, and prediction of survival from marital quality appeared stronger for female than for male patients. Thus, when marital quality and NYHA class are considered jointly, they both make independent, statistically significant contributions to the prediction of patient mortality.

摘要

越来越多的证据表明,社会支持与心血管疾病的更好预后及全因死亡率降低相关。关于婚姻功能对这些结果的具体贡献知之甚少,而且婚姻质量对充血性心力衰竭(CHF)的潜在预后意义尚未得到探讨。对189例CHF患者(139名男性和50名女性)及其配偶进行访谈和观察,以评估婚姻质量,并将其作为评估后48个月内患者生存的预测指标,并与基于疾病严重程度(纽约心脏协会[NYHA]分级)的预测进行比较。男性患者和女性患者的四年生存率分别为52.5%和68%。在Cox回归分析中,婚姻质量的综合指标对四年生存率的预测效果与患者同时期的NYHA分级相同(均p<0.001)。调整CHF严重程度并未削弱婚姻功能的预后意义,而且婚姻质量对女性患者生存率的预测似乎比对男性患者更强。因此,当同时考虑婚姻质量和NYHA分级时,它们对患者死亡率的预测都做出了独立的、具有统计学意义的贡献。

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