Huttary R, Verius M, Bodner G, Ennemoser O, Jaschke W
Universitäts-Klinik für Radiodiagnostik Innsbruck, Germany.
Ultraschall Med. 2001 Aug;22(4):159-62. doi: 10.1055/s-2001-16810.
The development of a computer controlled pump for the generation of variable flow patterns with high reproducibility for simulating the haemodynamics in physiological model circuits.
The module is controlled by an arbitrary function generator. The shape of the flow profile is generated on the PC based on mathematical functions or drawn by hand. The amplified signal drives a DC motor which is coupled magnetically to a geared pumphead. The lack of mechanical coupling ensures smooth running and a complete attenuation of motor vibrations as well as a disturbance-free flow profile. The spectra were analyzed by Doppler-sonography with a 5 - 12 MHz linear probe and with pressure sensors. Silicon tubes were used as simulated vessels and a water-glycerine mixture with particles of cellulose as simulated blood.
The generated flow patterns (constant flow and multi-phase patterns) correlate highly with the measured pressure- and velocity profiles.
The variability and high reproducibility of the flow profiles and the realtime control of the signal parameters make the simulation of dynamic processes and haemodynamic long-time studies feasible. The module developed facilitates detailed studies of high reproducibility with physiological and pathological flow models and with simulated blood.
开发一种计算机控制的泵，用于生成具有高再现性的可变流型，以模拟生理模型回路中的血流动力学。
该模块由任意函数发生器控制。流型的形状在计算机上基于数学函数生成或手工绘制。放大后的信号驱动一台直流电机，该电机通过磁力耦合到一个齿轮泵头。无机械耦合确保了运行平稳，电机振动完全衰减，以及流型无干扰。通过使用5 - 12 MHz线性探头的多普勒超声和压力传感器对频谱进行分析。用硅管作为模拟血管，用水 - 甘油混合物和纤维素颗粒作为模拟血液。
生成的流型（恒定流和多相流型）与测量的压力和速度分布高度相关。
流型的可变性和高再现性以及信号参数的实时控制使得动态过程的模拟和血流动力学长期研究成为可能。所开发的模块有助于使用生理和病理流模型以及模拟血液进行具有高再现性的详细研究。
