针对应激的自身细胞保护：血红素依赖性代谢的反馈调节
Self-cytoprotection against stress: feedback regulation of heme-dependent metabolism.
作者信息
Schwartsburd P M
机构信息
Institute of Theoretical and Experimental Biophysics, Russian Academy of Science, Moscow Region, Puschino.
出版信息
Cell Stress Chaperones. 2001 Jan;6(1):1-5. doi: 10.1379/1466-1268(2001)006<0001:scasfr>2.0.co;2.
Abstract
This minireview provides insight into feedback regulation of heme-dependent metabolism as a defensive cellular response against stress. Interactions among heme-, iron-, porphyrin-, and CO/NO-dependent metabolic pathways during the stress-induced response are emphasized in the context of feedback regulation. The hypothetical model of the latter interactions is presented as tightly controlled feedback cycles.
摘要
本综述深入探讨了血红素依赖性代谢的反馈调节，这是一种细胞对应激的防御反应。在反馈调节的背景下，强调了应激诱导反应期间血红素、铁、卟啉和一氧化碳/一氧化氮依赖性代谢途径之间的相互作用。后一种相互作用的假设模型表现为严格控制的反馈循环。
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