Newmark S R, Anderson C F, Donadio J V, Ellefson R D
Mayo Clin Proc. 1975 Jul;50(7):359-64.
Lipoproteins and lipoprotein profiles were determined in 96 adult nephrotic patients. The serum cholesterol-serum albumin, serum triglycerides-serum albumin and 24-hour urine protein loss-serum albumin values were all significantly inversely correlated. The serum triglycerides and serum cholesterol levels were not significantly lower in the group of lupus nephrotic patients compared to the nonlupus nephrotics. All lipoprotein types except type I were observed. The lipoprotein types fell into three nearly equal groups--IIa, IIb, and V. Type IV, the most common lipoprotein abnormality in uremic patients, was distinctly uncommon.
对96名成年肾病患者进行了脂蛋白和脂蛋白谱测定。血清胆固醇与血清白蛋白、血清甘油三酯与血清白蛋白以及24小时尿蛋白丢失与血清白蛋白值均呈显著负相关。与非狼疮性肾病患者相比，狼疮性肾病患者组的血清甘油三酯和血清胆固醇水平并无显著降低。除I型外，观察到了所有类型的脂蛋白。脂蛋白类型分为三个大致相等的组——IIa、IIb和V型。IV型是尿毒症患者最常见的脂蛋白异常类型，但在此明显不常见。
