Mitsuishi T, Kawashima M, Sata T
Department of Dermatology, Tokyo Women's Medical University, 8-1 Kawada-cho Shinjuku-ku, Tokyo 162-8666, Japan.
Eur J Dermatol. 2001 Sep-Oct;11(5):463-5.
We describe a case of Bowen's disease that developed on the left dorsal foot of a 56-year-old female patient and that mimicked the clinical features of a common wart. PCR-based analysis indicated that the lesion contained HPV-16 DNA and HPV-16 positive cells were found in the upper layers of the epidermal lesion using in situ hybridization with an HPV-16 probe.
我们报告一例发生于一名56岁女性患者左足背的鲍恩病，其临床表现酷似寻常疣。基于聚合酶链反应（PCR）的分析表明，该病变含有HPV-16 DNA，并且使用HPV-16探针进行原位杂交时，在表皮病变的上层发现了HPV-16阳性细胞。
